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ZOTERAN 200 mg Tablet; box of 30's (ANTIVIRAL ) ZOTERAN is Acyclovir, a synthetic guanine derivative with antiviral activity to Herpes simplex types I and II, and varic... (more) ZOTERAN is Acyclovir, a synthetic guanine derivative with antiviral activity to Herpes simplex types I and II, and varicella-zoster.
Used for infections caused by herpes simplex virus P type I & II including herpes in the skin and recurrent and chronic mucocutaneous, infection caused by varicella-zoster virus, secondary and primary of herpes genitalis. Available in 200mg Tablet in Aluminum Foil Strip of 10’s; Box of 30’s and 400mg Tablet in Foil strip of 4’s; Box of 12’s.
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MYODIAL 200mg Tablet; box of 30's (CARDIOVASCULAR/ANTIHYPERTENSIVE) MYODIAL is Amiodarone, used to correct abnormal rhythms of the heart (an antiarrhythmic medication). Amiodarone is consi... (more) MYODIAL is Amiodarone, used to correct abnormal rhythms of the heart (an antiarrhythmic medication). Amiodarone is considered a "broad spectrum" antiarrhythmic medication. Among its most important electrical effects are: a delay in the rate at which the heart's electrical system 'recharges' after the heart contracts(repolarization);a prolongation in the electrical phase during which the heart's muscle cells are electrically stimulated(action'potential); a slowing of the speed of electrical conduction (how fast each individual impulse is conducted through the heart's electrical system);a reduction in the rapidity of firing of the normal generator of electrical impulses in the heart (the heart's pacemaker);a slowing of conduction through various specialized electrical pathways(called accessory pathways)which can be responsible for arrythmias. In addition to being an antiarrhythmic medication, amiodarone also causes blood vessels to dilate(enlarge).This effect can result in a drop in blood pressure. Because of this effect it also may be of benefit in patients with congestive heart failure.
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AZIN 250mg Capsule; box of 6's (ANTIBACTERIAL) AZIN is Azithromycin, indicated in upper respiratory tract infections, including pharyngitis, tonsillitis, sinusitis, ot... (more) AZIN is Azithromycin, indicated in upper respiratory tract infections, including pharyngitis, tonsillitis, sinusitis, otitis media, lower respiratory tract infections including bronchitis, pneumonia; skin and soft tissue infections.
Azithromycin is also indicated in the treatment of uncomplicated genital infections due to Chlamydia trachomatis and uncomplicated gonnorrhoea from sexually transmitted diseases of men and women.
Azithromycin may also be used for prophylaxis in at-risk patients unable to take penicillins. Supplied in blister, box of 6's.
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EUROMAX 1g vial Powder for Inj.; box of 1's (ANTIBACTERIAL) EUROMAX is Cefepime hydrochloride, a semi-synthetic, broad-spectrum cephalosporin (4th generation) antibiotic for parent... (more) EUROMAX is Cefepime hydrochloride, a semi-synthetic, broad-spectrum cephalosporin (4th generation) antibiotic for parenteral administration. Cefepime hydrochloride is a white to pale yellow powder which is highly soluble to water. It also has an anti microbial action that acts by inhibition of bacterial cell wall synthesis. Available in type I clear glass vial + 10mL water for injection (diluent) in type 1 clear glass ampoule, box of 1's.
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FOTEXIN 1g vial Powder for Inj.; box of 1's (ANTIBACTERIAL) FOTEXIN is Cefotaxime, a broad spectrum bactericidal cephalosporin antibiotic. It has activity against a wide range of G... (more) FOTEXIN is Cefotaxime, a broad spectrum bactericidal cephalosporin antibiotic. It has activity against a wide range of Gram-positive and Gram-negative organisms. Cefotaxime is exceptionally active against Gram-negative organisms sensitive or resistant to first or second-generation cephalosporins. It is similar to other cephalosporins in activity against Gram-positive bacteria. Cefotaxime has a high degree of stability in the presence of beta lactamase both, penicillinase and cephalosporinases of Gram-negative and Gram-positive bacteria. The bactericidal activity of Cefotaxime results from inhibition of cell wall synthesis. Cefotaxime has been shown to distribute into a variety of tissues and body fluids and is excreted mainly through the kidney.
Used in the treatmenr of respiratory tract infections including nose and throat; acute and chronic bronchitis, pneumonia, infected bronchiectasis, lung abscess, and post-operatice chest infections. Supplied in 1g Powder for Injection in clear glass vial of 1’s and 10mL Water for Injection in clear glass ampoule (diluent) of 1’s; Box of 1’s.
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EUROFLAM 100mg Capsule; box of 50's (NSAIDS) EUROFLAM is Celecoxib, a non-steroidal anti-inflammatory drug. It is a highly selective COX-2 inhibitor and primarily in... (more) EUROFLAM is Celecoxib, a non-steroidal anti-inflammatory drug. It is a highly selective COX-2 inhibitor and primarily inhibits this isoform of cyclooxygenase (inhibition of prostaglandin production), whereas traditional NSAIDs inhibit both COX-1 and COX-2. Celecoxib is approximately 7.6 times more selective for COX-2 inhibition over COX-1. In theory, this specificity allows celecoxib and other COX-2 inhibitors to reduce inflammation (and pain) while minimizing gastrointestinal adverse drug reactions (e.g. stomach ulcers) that are common with non-selective.
Indicated in acute or chronic use in treatment of the signs and symptoms of osteoarthritis and rheumatoid arthritis. Available in 100mg and 200mg Capsules in PVC Alu blister packs of 10’s; Box of 50’s.
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LINCOX 200mg capsule; box of 50's (NSAIDS) LINCOX is Celecoxib, a non-steroidal anti-inflammatory drug. It is a highly selective COX-2 inhibitor and primarily inhi... (more) LINCOX is Celecoxib, a non-steroidal anti-inflammatory drug. It is a highly selective COX-2 inhibitor and primarily inhibits this isoform of cyclooxygenase (inhibition of prostaglandin production), whereas traditional NSAIDs inhibit both COX-1 and COX-2. Celecoxib is approximately 7.6 times more selective for COX-2 inhibition over COX-1. In theory, this specificity allows celecoxib and other COX-2 inhibitors to reduce inflammation (and pain) while minimizing gastrointestinal adverse drug reactions (e.g. stomach ulcers) that are common with non-selective.
Indicated in acute or chronic use in treatment of the signs and symptoms of osteoarthritis and rheumatoid arthritis. Available in 100mg and 200mg Capsules in PVC Alu blister packs of 10’s; Box of 50’s.
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PROBELIN 10g cream; box of 1's (ANTIINFLAMMATORY/ANTIPRURITIC) Clobetasol propionate is of particular value when used in short courses for the treatment of more resistant dermatoses s... (more) Clobetasol propionate is of particular value when used in short courses for the treatment of more resistant dermatoses such as psoriasis (excluding widespread plaque psoriasis), recalcitrant eczemas and other conditions which do not respond satisfactorily to less active steroids.
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EUROBEL 0.05% 10g tube; box of 1's (ANTIINFLAMMATORY/ANTIPRURITIC) EUROBEL is Clobetasol propionate, a small quantity should be applied to the affected area once or twice daily until impr... (more) EUROBEL is Clobetasol propionate, a small quantity should be applied to the affected area once or twice daily until improvement occurs. Therapy should be discontinued when control is achieved. It is recommended that treatment should not be continued for more than two or four weeks without the patient’s condition being reviewed. If continuous steroid treatment is required, a less potent preparation is required. Available in aluminum tube 10g, box of 1's.
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CURAFEN - K 50mg Film Coated Tablet; box of 50's (NSAIDS) CURAFEN K is Diclofenac Potassium, has a rapid onset of action, which makes it particularly suitable for the treatment o... (more) CURAFEN K is Diclofenac Potassium, has a rapid onset of action, which makes it particularly suitable for the treatment of acute painful and inflammatory conditions. Inhibition of prostaglandin biosynthesis is considered to be fundamental to its mechanism of action. Diclofenac is rapidly and completely absorbed from A-FENAC K tablets. The absorption sets in immediately after administration.
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CURAFEN 100mg Film Coated Tablet; box of 100's (NSAIDS) CURAFEN is Diclofenac Sodium, a potent nonsteroidal,anti-inflammatory agent with analgesic and antipyretic properties. B... (more) CURAFEN is Diclofenac Sodium, a potent nonsteroidal,anti-inflammatory agent with analgesic and antipyretic properties. By virtue of its analgesic,
antipyretic and anti-inflammatory properties together with its excellent tolerability marks a major advance in the treatment of rheumatic and or inflammatory conditions. Diclofenac inhibits cyclooxygenase activity with a reduction in the tissue production of prostaglandins such as PGE1 and PGE2.
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GASTRODIN 10 mg Film Coated Tablet; box of 30's (ANTI-SPASMODIC/ ANTI-FLATULENT) GASTRODIN is Domperidone, a dopamine agonist with antiemetic properties similar to those of metoclopramide. Antiemetic e... (more) GASTRODIN is Domperidone, a dopamine agonist with antiemetic properties similar to those of metoclopramide. Antiemetic effect maybe due to combination of peripheral effects and antagonism of dopamine receptors in the chemorceptor trigger zone, which lies outside the blood brain barrier in the postrema area. Domperidone increases the duration of antral and duodenal contractions, gastric emptying of liquids and solids and lower esophageal sphincter pressure.
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DOXY-A 100mg Capsule; box of 100's (ANTIBACTERIAL) Doxy as Doxycycline, is highly active broad-spectrum antibiotic of tetracycline group. It is effective against wide rang... (more) Doxy as Doxycycline, is highly active broad-spectrum antibiotic of tetracycline group. It is effective against wide range of Gram-positive and Gram-negative bacteria, spirochete, mycoplasma, rickettsia and mycobacteria. It is used as an alternate to penicillin in the treatment of gonorrhoea and syphilis. Doxycycline has its main mechanism of action on protein synthesis. Inside the bacterial cell, it inhibits protein synthesis. Supplies in blister box of 100's.
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RIXOFEN 120mg Tablet; box of 30's (ANTIHISTAMINE) RIXOFEN (Fexofenadine) Fexofenadine hydrochloride is a non-sedating H1 antihistamine. Fexofenadine is a pharmacologicall... (more) RIXOFEN (Fexofenadine) Fexofenadine hydrochloride is a non-sedating H1 antihistamine. Fexofenadine is a pharmacologically active metabolite of terfenadine.
Human histamine wheal and flare studies following single and twice daily doses of fexofenadine hydrochloride demonstrate that the drug exhibits an antihistaminic
effect beginning within one hour, achieving maximum at 6 hours and lasting 24
hours. There was no evidence of tolerance to these effects after 28 days of dosing. A
positive dose-response relationship between doses of 10 mg to 130 mg taken orally
was found to exist. In this model of antihistaminic activity, it was found that doses of
at least 130 mg were required to achieve a consistent effect that was maintained over a 24 hour period. Maximum inhibition in skin wheal and flare areas were
greater than 80%. Clinical studies conducted in allergic rhinitis have shown that a
dose of 120 mg is sufficient for 24 hour efficacy.
No significant differences in QTc intervals were observed in seasonal allergic rhinitis
patients given fexofenadine hydrochloride up to 240 mg twice daily for 2 weeks
when compared to placebo. Also, no significant change in QTc intervals was observed in healthy subjects given fexofenadine hydrochloride up to 60 mg twice daily for 6 months, 400 mg twice daily for 6.5 days and 240 mg once daily for 1 year, when compared to placebo. Fexofenadine at concentrations 32 times greater than the therapeutic concentration in man had no effect on the delayed rectifier K+ channel cloned from human heart.
Fexofenadine hydrochloride (5-10 mg/kg po) inhibited antigen induced
bronchospasm in sensitized guinea pigs and inhibited histamine release at
supratherapeutic concentrations (10-100um) from peritoneal mast cells.
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MIGRALIN 5mg Tablet; box of 30's (ANTIMIGRAINE) MIGRALIN( Flunarizine), a difluorinated derivative of Cinnarizine. Flunarizine is a selective calcium channel antagonist... (more) MIGRALIN( Flunarizine), a difluorinated derivative of Cinnarizine. Flunarizine is a selective calcium channel antagonist. It prevents cellular calcium
overload by reducing excessive transmembrane influxes of calcium. It does not interfere with normal cellular calcium hemostasis. It has also
antihistaminic and sedative properties.
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SENTIONYL 5mg Tablet; box of 100's (ANTIDIABETIC AGENT) SENTIONYL is Glibenclamide, a second generation sulphonylurea. Glibenclamide (Sentionyl) is used in the management of no... (more) SENTIONYL is Glibenclamide, a second generation sulphonylurea. Glibenclamide (Sentionyl) is used in the management of non-insulin dependent diabetes mellitus (NIDDM). Glibenclamide (Sentionyl) causes degranulation of the =538;-cells in the pancreas resulting in insulin secretion and increases the number of insulin receptors in fat, skeletal muscle and liver. In both short term and long term administration in diabetes, Glibenclamide (Sentionyl) maintains the glucose level in body by reducing the blood glucose level. Glibenclamide (Sentionyl) is indicated in the treatment and control of blood sugar in non-insulin dependent diabetes mellitus (NIDDM) patients, when hyperglycemia is not adequately controlled by diet alone. Glibenclamide (Sentionyl) is only indicated to NIDDM patients.
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GLIVARID 1mg tablet; box of 50's (ANTIDIABETIC AGENT) GLIVARID is an oral hypoglycemic drug belonging to the sulfonylurea group. It stimulates the release of insulin from fun... (more) GLIVARID is an oral hypoglycemic drug belonging to the sulfonylurea group. It stimulates the release of insulin from functioning pancreatic ^6;-cells. It also can increase sensitivity of peripheral tissues to insulin. Indicated in type 2 diabetes mellitus when dietary modification has failed in adequate glycemic control. Available in blister pack of 10's, box of 50's.
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GLIVARID 2mg tablet; box of 40's (ANTIDIABETIC AGENT) GLIVARID is an oral hypoglycemic drug belonging to the sulfonylurea group. It stimulates the release of insulin from fun... (more) GLIVARID is an oral hypoglycemic drug belonging to the sulfonylurea group. It stimulates the release of insulin from functioning pancreatic ^6;-cells. It also can increase sensitivity of peripheral tissues to insulin. Indicated in type 2 diabetes mellitus when dietary modification has failed in adequate glycemic control. Available in blister pack of 10's, box of 40's.
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GLIVARID 3mg tablet; box of 30's (ANTIDIABETIC AGENT) GLIVARID is an oral hypoglycemic drug belonging to the sulfonylurea group. It stimulates the release of insulin from fun... (more) GLIVARID is an oral hypoglycemic drug belonging to the sulfonylurea group. It stimulates the release of insulin from functioning pancreatic ^6;-cells. It also can increase sensitivity of peripheral tissues to insulin. Indicated in type 2 diabetes mellitus when dietary modification has failed in adequate glycemic control. Available in blister pack of 10's, box of 30's.
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FUNGIZOL 200mg Film Coated Tablet; box of 50's (ANTIFUNGAL ) FUNGIZOL is Ketoconazole, an imidazole antifungal which interferes with ergosterol synthesis and therefore alters the pe... (more) FUNGIZOL is Ketoconazole, an imidazole antifungal which interferes with ergosterol synthesis and therefore alters the permeability of the cell membrane of sensitive fungi. It has a wide spectrum of antimicrobial activity including activity against Blastomyces dermatidis, Candida spp., Coccidioides immitis, Epidermophyton floccosum, Histoplasma capsulatum, Malassezia spp., Microsporum canis, Paracoccidioides brasiliensis, Trichophyton mentagrophytes, T. rubum.
Indicated in the treatment of chronic mucocutaneous candidiasis, fungal infections of the gastrointestinal tract, dermatophyte infections of the skin and fingernails not responding to topical treatment, and in systemic infections including blastomycosis, candidiasis, coccidioidomycosis, histoplasmosis and paracoccidioidomycosis. Available in blister pack of 10’s; Box of 50’s.
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EUROLAC 10mg Film Coated Tablet; box of 20's (NSAIDS) EUROLAC is Ketorolac trometamol, a potent analgesic agent of non-steroidal, anti-inflammatory class (NSAID). Its mode of... (more) EUROLAC is Ketorolac trometamol, a potent analgesic agent of non-steroidal, anti-inflammatory class (NSAID). Its mode of action is to inhibit the cyclo-oxygenase enzyme system and hence prostaglandin synthesis, and it demonstrates a minimal anti-inflammatory effect at its analgesic dose. Eurolac is not an anesthetic agent and possesses no sedative or anxiolytic properties; therefore it is not recommended as a pre-operative medication for the support of anesthesia when these effects are required. It is not an opioid and has no known effects on opioid receptors.
Indicated for the short-term management of postoperative pain. Available in blister pack of 10’s; Box of 20’s.
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LANSODIN 30mg Capsule; box of 28's (ANTI-ULCER DRUGS) LANSODIN is Lonsoprazole, a proton pump inhibitor. It is an irreversible inhibitor of the parietal cell H+ - K+ ATPase, ... (more) LANSODIN is Lonsoprazole, a proton pump inhibitor. It is an irreversible inhibitor of the parietal cell H+ - K+ ATPase, which leads to profound inhibition of gastric acid secretion. It blocks the final step of acid production. This effect is dose-related and leads to inhibition of both basal and stimulated gastric secretion irrespective of the stimulus. Available in alu-alu blister of 4's, box of 28's.
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EUROLEV 50mcg Tablet; box of 90's (ANTIHYPOTHYROIDISM) EUROLEV is Levothyroxine sodium, it is used as replacement therapy in the treatment of hypothyroidism, to suppress TSH p... (more) EUROLEV is Levothyroxine sodium, it is used as replacement therapy in the treatment of hypothyroidism, to suppress TSH production in the treatment of thyroid carcinoma and as a diagnostic agent for the differential diagnosis of hypothyroidism.
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MEPRALIN 20mg Capsule; box of 20's (ANTACIDS & ANTIULCERANTS) Omeprazole (Mepralin), the substituted benzimadole, is an inhibitor of gastric acid secretion. Omeprazole does not exhib... (more) Omeprazole (Mepralin), the substituted benzimadole, is an inhibitor of gastric acid secretion. Omeprazole does not exhibit anticholinergic or H2-histamine antagonistic properties, but inhibits the secretion of gastric acid by blocking the H+/K+ATPase (hydrogen-potassium-adenosine triphosphatase) enzyme system, the so-called “proton pump” of the gastric parietal cell.
After oral administration of Omeprazole (Mepralin) absorption is rapid, onset occurs within 1 hour and peaks within 2 hours. Inhibition of secretion is about 50% of maximum at 24 hours, and the duration of inhibition lasts not longer than 72 hours. The antisecretory effect thus lasts far longer than would be expected from the very short (<1 hour) plasma half-life, apparently due to prolonged binding to the parietal H+K+ATPase enzyme. When the drug is discontinued, secretory activity return over 3 to 5 days.
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HYPERGO 4mg Tablet; box of 30's (CARDIOVASCULAR/ANTIHYPERTENSIVE) NOVARIL (Perindopril) acts as a prodrug of the diacid perindoprilat, its active form. Following oral administration peri... (more) NOVARIL (Perindopril) acts as a prodrug of the diacid perindoprilat, its active form. Following oral administration perindopril is rapidly absorbed and extensively metabolised, mainly in the liver, to perindoprilat and inactive metabolites including glucuronides. The presence of food is reported to reduce the conversion of perindopril to perindoprilat. Peak plasma concentrations of perindoprilat are achieved 3 to 4 hours after an oral dose of perindopril. Perindoprilat is about 10 to 20% bound to plasma proteins. About 75% of an oral dose of perindopril is excreted in the urine as unchanged drug, as perindoprilat, and as other metabolites; the remainder is excreted in the faeces. The elimination of perindoprilat is biphasic with a distribution half-life of about 5 hours and an elimination half-life of 25 to 30 hours, the latter half-life probably representing strong binding to angiotensin-converting enzyme. The excretion of perindoprilat is decreased in renal impairment. Both perindopril and perindoprilat are removed by dialysis.
Indications:
Indicated for the treatment of patients with essential and renovascular hypertension.
Congestive heart failure (adjunctive therapy).
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NOVARIL 4mg tablet; box of 30's (CARDIOVASCULAR/ANTIHYPERTENSIVE) NOVARIL is Perindopril erbumine, the tert-butylamine salt of perindopril, the ethyl ester of a non-sulfhydryl angiotensi... (more) NOVARIL is Perindopril erbumine, the tert-butylamine salt of perindopril, the ethyl ester of a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor. Perindopril is the free acid form of perindopril erbumine, is a pro-drug and metabolized in vivo by hydrolysis of the ester group to form perindoprilat, the biologically active metabolite. It is a competitive inhibitor of angiotensin-converting enzyme (ACE); prevents conversion of angiotensin I to angiotensin II, a potent vasoconstrictor; results in lower levels of angiotensin II which, in turn, causes an increase in plasma renin activity and a reduction in aldosterone secretion
The mechanism through which perindoprilat lowers blood pressure is believed to be primarily inhibition of ACE activity. Inhibition of ACE results in decreased plasma angiotensin II, leading to decreased vasoconstriction, increased plasma renin activity and decreased aldosterone secretion. The latter results in diuresis and natriuresis and may be associated with a small increase of serum potassium.
While the principal mechanism of perindopril in blood pressure reduction is believed to be through the renin-angiotensin-aldosterone system, ACE inhibitors have some effect even in apparent low-renin hypertension.
Indicated for essential and renovascular hypertension; congestive heart failure. Available in blister pack of 10’s in aluminum pouch; Box of 30’s.
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BURNSIL 25g cream; box of 1's (ANTIBACTERIAL) Silver Sulfadiazine is a local chemotherapeutic for prevention and treatment of burn wound infections. Silver Sulfadia... (more) Silver Sulfadiazine is a local chemotherapeutic for
prevention and treatment of burn wound infections. Silver
Sulfadiazine disintegrates in the burn wound, thereby causing
a slow and sustained release of silver ions. Silver ions bind to
bacterial deoxyribonucleic acid, thus inhibiting the growth and
multiplication of bacterial cells without affecting the cells of the
skin and subcutaneous tissue. Silver sulfadiazine cream has a broad
antibacterial spectrum including virtually all microbial species
likely to infect the burn wound: Escherichia coli, Pseudomonas
aeruginosa, Staphylococcus aureus, strains of Proteus and
Klebsiella; it is also effective against Candida albicans and
other fungi. Silver Sulfadiazine cream penetrates into the
necrotic tissue and exudate. This effect is very important in
view of the fact that systemic antibiotics are not effective
against the bacterial flora of vascular burn necrosis.
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